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August 27, 2014
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The European Society of Cardiology (ESC) 2014 Congress will be held in Barcelona, Spain from August 30-September 3, 2014.
Major presentations at this year's conference include details from LCZ696's (NVS) PARADIGM-HF positive outcomes trial in heart failure and Phase III data from PCSK9 inhibitor alirocumab (REGN, SNY), where an extension trial showed a reduction in major adverse cardiovascular events (MACE). One hot-line session will also have proof-of-concept results for TRO40303 (Trophos), a novel mitochondria pore modulator for acute myocardial infarction, but it has not been released whether results are positive or negative. We have assembled a full pre-meeting planner listing talks and posters. In addition to the above, we have highlighted various other presentations with some background and where available, results, including: Acute Coronary Syndrome and Coronary Artery Disease
Major presentations at this year's conference include details from LCZ696's (NVS) PARADIGM-HF positive outcomes trial in heart failure and Phase III data from PCSK9 inhibitor alirocumab (REGN, SNY), where an extension trial showed a reduction in major adverse cardiovascular events (MACE). One hot-line session will also have proof-of-concept results for TRO40303 (Trophos), a novel mitochondria pore modulator for acute myocardial infarction, but it has not been released whether results are positive or negative. We have assembled a full pre-meeting planner listing talks and posters. In addition to the above, we have highlighted various other presentations with some background and where available, results, including: Acute Coronary Syndrome and Coronary Artery Disease
- Ivabradine's (Servier, AMGN) SIGNIFY in stable CAD
- In ambulance treatment with Ticagrelor (AZN, MDCO; ATLANTIC study)
- Darapladib's (GSK) failed SOLID-TIMI 52.
- Details on ISIS-APO(a)Rx's Phase I study
- First-in-man study of small molecule aripazine (Perosphere) to reverse factor X anti-coagulants
- X-VERT: rivaroxaban (JNJ, BAYRY) versus warfarin for early or late cardioversion
- Favorable effects of dabigatran on renal function (Boehringer)
- Phase II results for SDF-1 (Juventas), plasmid stromal cell-derived factor 1
- One-year results from riociguat's (BAYRY, MRK) PATENT-2
- Vagal stimulation for heart failure (NECTAR-HF and ANTHEM-HF)
- Biventricular pacing for routine pacing indications (St. Jude)
- Stents: Orsiro biodegradable polymer (Biotronik), Cobra PzF (CeloNova), Bioresorbable PLLA/ACP scaffold (Vasotech)
- Value of treating non-culprit lesions with PCI during STEMI (CvLPRIT)
- One year results from Medtronic's renal denervation trial, SYMPLICITY HTN (6 months results were negative)
Disease Group Covered: | Cardiovascular |
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