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Datamonitor Asthma and COPD KOL Interview

February 29, 2016

Datamonitor interviewed a pulmonologist based in Boston, MA to determine their current treatment practices and opinions on late-stage pipeline drugs for the treatment of COPD and asthma.

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Highlights
  • KOL thinks that the biggest challenge to treating COPD is cost, even with a very low population of uninsured people.
  • He likes simpler drugs for COPD patients for compliance reasons. Once a day is best and three times is just too much.
  • He prescribes more LABA/LAMA drugs earlier than Gold Guidelines; doesn’t adhere to them strictly but teaches them.
  • KOL says that Respimat is a very good aerosol device, but he generally prefers the dry powder devices (Boehringer).
  • He would generally start COPD patients on Breo Ellipta over Advair if insurance will pay for it (GSK).
  • Spiriva has been a good drug, and it will be hard to displace without some specific advantage (Boehringer).
  • Physicians are skeptical of PDE4 drug, Daliresp, and people are going with theophyllines despite slightly worse side effect profile (AZN).
  • KOL does not believe approval for Spiriva for asthma will change his use. He’s been using it off-label for a long time (Boehringer).
  • He uses Xolair to treat asthma and thinks it is safe. The malignancy risks have been largely disproven (Roche).
  • KOL does not believe that IL-5 inhibitors will be a panacea in asthma patients and will only be used in a small subset of patients (GSK, AZN).
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Disease Group Covered: Respiratory

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