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2016 Biomedtracker / Datamonitor Healthcare ADA Planner
June 02, 2016
The American Diabetes Association (ADA) 76th Scientific Sessions will be held in New Orleans, LA from June 10-14, 2016. Abstracts will
not be on line until June 3 after 5 PM EST.
The most notable presentation this year is data from GLP-1 agonist Victoza's (NVO) cardiovascular outcomes trial (CVOT). The SGLT2
inhibitor Jardiance (Boehringer, LLY), which had positive data from its CVOT released at conferences last year, will have an update at the
ADA, and it will be quite interesting to compare results from the trials. While Jardiance’s benefit on its primary endpoint was mostly
derived
from a reduction in CV death, Novo Nordisk stated that all three components of the endpoint (CV death, non-fatal myocardial infarction
and
non-fatal stroke) contributed to Victoza's overall reduction in CV risk. There will also be first Phase III data or first conference
presentations
from a number of drugs or studies, including ertugliflozin (MRK, PFE), semaglutide's SUSTAIN 2 and 3 (NVO), ITCA 650's FREEDOM-2
(Intarcia, Servier), the biosimilar insulins MK-1293 (MRK) and SAR342434 (SNY), and faster-acting insulin aspart (NVO).
Drugs/Devices Highlighted:
- GLP-1 Agonists versus SGLT2 Inhibitors, CVOTs and Renal Effects: Victoza (NVO), Jardiance (Boehringer, LLY), Invokana (JNJ)
- Other SGLT2 Inhibitor Highlights: Ertugliflozin (MRK, PFE), Farxiga (AZN), Invokana (JNJ)
- Other GLP-1 Agonist Highlights: Semaglutide (NVO), ITCA 650 (Intarcia, Servier), Victoza (NVO)
- GLP-1 Agonist – Insulin Combination Treatment: Xultophy (NVO), LixiLan (SNY)
- Insulins: MK-1293 (MRK), SAR342434 (SNY), Tresiba (NVO), faster-acting insulin aspart (NVO), BioChaperone lispro (LLY, Adocia)
- Early Stage Drugs: MEDI4166 (AZN), MK-8666 (MRK), PF-06293620 (PFE), PF-06291874 (PFE)
- Devices: Dexcom CGM
Indications Covered: |
Diabetes Mellitus, Type I
Diabetes Mellitus, Type II Diabetic Nephropathy Dyslipidemia / Hypercholesterolemia Obesity |