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2016 Biomedtracker / Datamonitor Healthcare AHA Planner
November 08, 2016
The American Heart Association (AHA) Scientific Sessions will be held in New Orleans, LA from 12–16 November 2016.
This year's conference features a number of prominent data presentations. One late-breaking session on lipid trials features interesting
new
details from
PCSK9 inhibitor studies, including atherosclerosis imaging from Repatha's (evolocumab; Amgen/Astellas) GLAGOV trial and extended
dosing
data from
PCSK9si (The Medicines Company/Alnylam). New Phase III heart failure data for ularitide (Cardiorentis) are also highly anticipated. The
data
were
supposed to be presented at the last American College of Cardiology meeting, but there were last-minute issues that the investigators
wanted to
fully
validate. While Xarelto (rivaroxaban; Bayer/Johnson & Johnson) has struggled in the acute coronary syndrome indication, there will be
new data
on its use
in patients undergoing percutaneous coronary intervention (PCI) who have atrial fibrillation, which could prove successful for the drug as
it is
being
compared to vitamin K antagonists. On the device front, investigational device exemption (IDE) study data on HeartMate 3 (St. Jude
Medical)
versus
HeartMate 2 will help determine if changes to the left-ventricular assist device (LVAD) have led to the hoped-for improvements.
Drugs/Devices Highlighted:
- Dyslipidemia: Repatha (AMGN, Astellas), PCSK9si (MDCO, ALNY, ABUS), CSL112 (CSL Limited), MDCO 216 (MDCO, PFE), Evinacumab (REGN)
- Heart Failure: Ularitide (Cardiorentis, PDLI, Pharis), Injectafer (Daiichi, Galenica, Fresenius, Zeria), HeartMate 3 (STJ)
- Anticoagulation: Xarelto (BAYRY, JNJ), Pradaxa (Boehringer)
- Antiplatelet Therapy: Brilinta (AZN, MDCO)
- Cardiovascular Outcomes Trial in Type 2 Diabetes: Jardiance (Boehringer, LLY), Victoza (NVO)
- Cell Therapy: MarrowStim (ZBH)
Indications Covered: |
Acute Coronary Syndrome (ACS)
Acute Decompensated Heart Failure - Reduced Ejection Fraction (Acute HFrEF) Anemia Anticoagulation Chronic Heart Failure - Reduced Ejection Fraction (Chronic HFrEF) Diabetes Mellitus, Type II Dyslipidemia / Hypercholesterolemia Peripheral Arterial Disease (PAD) Stroke Prevention in Atrial Fibrillation (SPAF) |
Additional Resources: