Dengue fever is an emerging flaviviral infection transmitted mainly by Aedes aegypti and Aedes albopictus mosquitoes. The dengue burden has expanded rapidly over the last few decades, and the disease is now endemic in many Latin American and Asia-Pacific countries, with 75% of the at-risk population residing in the latter region. Dengue usually manifests as a severe flu-like illness, with symptoms including headache, retro-orbital pain, muscle pain, and vomiting, but 1–3% of infections will manifest as dengue hemorrhagic fever, characterized by plasma leakage, severe bleeding, and respiratory distress.

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